Dr. Vaibhav Wasnik, Post-doctoral Fellow at University of Saarland
Event Date: 
Thursday, 21 January 2016 - 4:00pm to 5:00pm
Title: Protein localization in biological systems.                                                                                                                                                                                                                                                                                                                                                                        Abstract: Cells are required to respond to spatially localized signals so as to move in the direction of nutrition, move away from danger etc. This is accomplished using proteins that localize to certain cellular regions. Examples include actin involved in cell locomotion and Protein Kinase C involved in cell signaling. In spite of its overwhelming importance it is not well understood how localization is achieved. In this talk we present two specific examples of protein localization. The first part of the talk will outline an uncertainity relation in calcium signal detection by analyzing the role played by the Protein Kinase C (PKC) in calcium signal transduction. The second part of the talk will focus on actin self-organization with the presentation of a physical model for phagocytic actin waves in Dictyostelium. Our results highlight the importance of collective effects and the need for physical analysis for understanding cell behavior.  
Venue: 
Departmental Library, Physics Department (2nd floor)
IIT Bombay, Powai, Mumbai