Amitabha Nandi
Assistant Professor
Research Interests: 

The research in my group focuses on the physics of biological systems. We study biophysical processes at the sub-cellular, cellular and tissue scales using theoretical and computational techniques. We are interested in understanding how an observed physical or mechanical process is regulated by the underlying bio-chemical process(es) and vice versa. To do this, we use methods from statistical physics, nonlinear dynamics and soft-matter physics. Specific areas of research include: (1) Dynamical behavior of bio-chemical processes inside cells. (2) To understand cellular functions by studying active and passive transport of cargo molecules inside cells. (3) Study of tissue remodeling and cellular flow patterns during the development of an organism.

Research projects:

  • Active mechanics and dynamics of epithelia during morphogenesis.
  • Collective cell migration during body-axis elongation in developing embryos.
  • Mechanisms of kinetochore capture by spindle microtubules during cell-division.
  • Anomalous cargo transport inside cells.
  • Mechanisms of micro-RNA regulation.

Besides, we are also interested in studying models of nonlinear dynamical systems, both discrete and time-continuous, under the effect of parametric modulation, external forcing, or coupling with other systems. The motivation arises from the fact that dynamical systems in nature are rarely isolated: such modulations can give rise to interesting phenomena that are absent in the unforced system.

Selected Publications: 
  • Active dynamics of tissue shear flow.
    Marko Popović, Amitabha Nandi, Matthias Merkel, Raphaël Etournay, Suzanne Eaton, Frank Jülicher, Guillaume Salbreux.
    New Journal of Physics, 19, 033006 (2017).
Research Category: